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Hello so my dog was diagnosed with cussins...

Resolved • Response time 2 minutes

28 Nov 2021

Hello so my dog was diagnosed with cussins disease and diabetes a year and a half ago.
We kept him well on insulin until 2 weeks ago he started to pass blood from urine and had diorreah.
He got weak and the evening he died he was shaking well before and havin seizures.
What would have been the cause so sudden
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28 Nov 2021

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Dog Specialist's response
28 Nov 2021
Dr. Michael Salkin
Dr. Michael Salkin
Veterinarian

Dr. Michael Salkin is typing. Please be patient.

28 Nov 2021
Dog Specialist's response
28 Nov 2021
Dr. Michael Salkin
Dr. Michael Salkin
Veterinarian

My condolences for your loss. Was he also being treated for his Cushing's disease with either trilostane or mitotane?

28 Nov 2021
Customer reply
28 Nov 2021
He wasent being treated for Cushings but the diabetes injection morning and night really kept him going.
It was just the way he lost weight and lost appetite and died so suddenly which really was upsetting to see a home death
28 Nov 2021
Dog Specialist's response
28 Nov 2021
Dr. Michael Salkin
Dr. Michael Salkin
Veterinarian

There are a number of considerations.

The hematuria (blood in the urine) is most often due to bacterial urinary tract infection common in both diabetics and cushingoid dogs.

Seizures are most often caused by an enlarging pituitary tumor - the most common cause of Cushing's disease; or metastasis from an adrenal tumor causing his Cushing's disease.

Cushing's and diabetes are also thromboembolic (clot producing). Clots in the brain can cause seizures. Clots in the lungs are often rapidly life-threatening.

Finally, both of these diseases affect all of the body systems and so it's reasonable to assume that he suffered from multiple organ failure.

Please continue in this conversation if you wish.

28 Nov 2021
Customer reply
28 Nov 2021
Okay cool so with the multiple organ failure would this most likely be from the cushings and diabetes together.
Also if we had got him to the vets a couple of days earlier would it still have been too late
28 Nov 2021
Customer reply
28 Nov 2021
Also as he was dying he put out a loud disturbing like yawn sound
28 Nov 2021
Dog Specialist's response
28 Nov 2021
Dr. Michael Salkin
Dr. Michael Salkin
Veterinarian

Correct. That's an awful combination of diseases.

It's very unlikely that his vet would have been able to be of value. That sound is agonal - indicative of impending death and likely due to anginal pain from a failing heart.

28 Nov 2021
Customer reply
28 Nov 2021
Aaaw that’s so sad hope he diddnt feel too much pain in the end moments
28 Nov 2021
Customer reply
28 Nov 2021
basically old age got him in the end
28 Nov 2021
Dog Specialist's response
28 Nov 2021
Dr. Michael Salkin
Dr. Michael Salkin
Veterinarian

Yes, these are diseases of older dogs.

28 Nov 2021
Customer reply
28 Nov 2021
Well thanks makes me feel better as we diddnt ask the vets what the cause was
28 Nov 2021
Customer reply
28 Nov 2021
Much appreciated
28 Nov 2021
Customer reply
28 Nov 2021
Also would he have been aware while having shakes and seizures
28 Nov 2021
Dog Specialist's response
28 Nov 2021
Dr. Michael Salkin
Dr. Michael Salkin
Veterinarian

...not during the seizure but perhaps just prior and afterward..

28 Nov 2021
Customer reply
28 Nov 2021
Okay thanks after he had the very last seizure he stood up and looked me in the eyes and just went it was like he knew
28 Nov 2021
Customer reply
28 Nov 2021
Thanks though for the answers, take care
28 Nov 2021
Dog Specialist's response
28 Nov 2021
Dr. Michael Salkin
Dr. Michael Salkin

You're quite welcome.

Customer rating:
Dr. Michael Salkin
Dr. Michael Salkin
Veterinarian
Avg. question only £30
University of California at Davis graduate veterinarian with 48 years of experience
28 Nov 2021
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